Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. Rev Med Brux 2008;29(5):490-493. Aldosterone is a hormone that causes your body to retain salt (sodium) and lose potassium. This could change the effects and side effects of these medications. Goto, F., Asama, Y., and Ogawa, K. Sho-saiko-to-ka-kikyo-sekko as an alternative treatment for chronic tonsillitis to avoid surgery. Xu, L., Jiang, J., and Du, F. Z. View abstract. Acharya SK, Dasarathy S, Tandon A, et al. Licorice that has the active ingredient of glycyrrhiza can have serious side effects. View abstract. 2017 Apr 1;27(2):150-154. doi: 10.1684/ejd.2016.2946. It's thought liquorice's side-effects are caused by the glycyrrhizic acid, but it is possible to buy deglycyrrhizinated liquorice (DGL), which may help prevent these issues. View abstract. This information may not fit your specific health circumstances. Evid Based Complement Alternat Med 2016;2016:9852793. View abstract. BMJ Case Rep. 2013 Sep 19;2013. Planta Med 1991;57(2):119-121. It is often used together with peony, which can significantly enhance . Kim YR, Nam SH. View abstract. View abstract. View abstract. View abstract. Kormann R, Languille E, Amiot HM, Hertig A. View abstract. View abstract. Wu G, Wu N, Li T, et al. View abstract. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Cancer Lett 12-10-2001;174(1):17-24. Wilson, J. Intern Med 2007;46:575-8. Postgrad Med J 2003;79:115-6.. View abstract. Complement Ther Clin Pract. Efficacy and tolerability of hydroalcoholic extract of Paeonia officinalis in children with intractable epilepsy: An open-label pilot study. J Assoc Physicians India 1989;37(10):647. 2020 Dec;58(1):352-356. Report of a new case]. 2013 Sep;117(3):614-21. View abstract. Chemical studies of Chinese licorice-roots. View abstract. View abstract. Inhibition of 11 beta hydroxysteroid dehydrogenase obtained from guinea pig kidney by furosemide, naringenin and some other compounds. [Clinical study on effect of recombinant roasted licorice decoction combined with low-dose glucocorticoids in treating idiopathic thrombocytopenic purpura]. Too much black licorice, the federal agency says, can lead to "abnormal heart rhythms, as well as high blood pressure, edema (swelling), lethargy, and congestive heart failure." . Bai, Y. S., Zhou, C. Y., and Wang, J. Q. Das SK, Das V, Gulati AK, and et al. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. 2011;25(1-2):21-38. Effects of Paeonia lactiflora root extracts on the secretions of monocyte chemotactic protein-1 and -3 in human nasal fibroblasts. Licorice extract inhibits the production of tyrosinase, in turn inhibiting the production of dark spots. Plant Description. Shen, A. Y., Wang, T. S., Huang, M. H., Liao, C. H., Chen, S. J., and Lin, C. C. Antioxidant and antiplatelet effects of dang-gui-shao-yao-san on human blood cells. Taking licorice along with "water pills" might make potassium levels drop too low. Shintani, S., Murase, H., Tsukagoshi, H., and Shiigai, T. Glycyrrhizin (licorice)-induced hypokalemic myopathy. Deglycyrrhizinated liquorice in aphthous ulcers. View abstract. Ann Noninvasive Electrocardiol. J Clin Pharm Ther 2002;27:229-30. . View abstract. 2012;18(4):534-543. View abstract. Immediately afterwards, Teacher Liu looked at her, picked up her paper, and said, Student Zhou Xiaotong, this time I ll give you a warning. View abstract. Chen, W. G. and Ba, Z. M. Prof. ZHANG Yi's experience in treating severe arrhythmia. 2020;45(2):257-264. J Contemp Dent Pract 2010;11(1):E088-E094. Steroids 2005;70(8):538-542. Licorice might change how these pumps work and change how much medication stays in the body. View abstract. White peony ( bai shao in Chinese) is root without any bark, while red peony . Learn more about Peony health benefits, uses, side effects, effectiveness, safety, precautions, and warnings. View abstract. Licorice or Mulethi, also known as "Sweetwood", is an effective and potent medicinal herb. Tooth decay. View abstract. A., Braun, T. M., and Jacobson, J. J. ""- . N Engl J Med 1991;325:1223-7. J Cancer Res Ther. Sigurjonsdottir, H. A., Manhem, K., Axelson, M., and Wallerstedt, S. Subjects with essential hypertension are more sensitive to the inhibition of 11 beta-HSD by liquorice. Phytomedicine 2003;10:271-85. Zhang XH, Lowe D, Giles P, et al. The effect of dong quai on menopausal symptoms is unknown. Xu Y, Li X, Chen T, et al. View abstract. View abstract. Li C, Wang ZB. J Assoc Physicians India 1978;26(9):811-814. Licorice, tobacco chewing, and hypertension. Lee YS, Lorenzo BJ, Koufis T, et al. Eisenburg, J. Fermented milk containing Lactobacillus paracasei and Glycyrrhiza glabra has a beneficial effect in patients with Helicobacter pylori infection: a randomized, double-blind, placebo-controlled study. Double-blind, placebo-controlled, randomized, pilot clinical trial of ImmunoGuard--a standardized fixed combination of Andrographis paniculata Nees, with Eleutherococcus senticosus Maxim, Schizandra chinensis Bail. View abstract. Endocrinol Jpn 1991;38(2):167-174. Medicine (Baltimore) 2019;98(35):e16601. The effect of a traditional Chinese prescription for a case of lung carcinoma. 5-10-2004;208(1):89-94. Yasue H, Itoh T, Mizuno Y, Harada E. Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. Licorice roots can be consumed directly to get relief from cough and sore throat. Licorice is Sita (cold) in nature, Guru (heavy) to digest, and Madhura (sweet) in . Effects of total glucosides of peony on immunological hepatic fibrosis in rats. Licorice reduces body fat mass in obese men and women. Biol Pharm Bull 2007;30(11):2191-2195. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. View abstract. Riv Patol Nerv Ment 1983;104(4):179-183. Gibertoni, M., Bonito, V., Colombo, A., Falasca, A., and Nichelli, P. [Licorice-induced myopathy. View abstract. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Additional reporting by Meghan De Maria. View abstract. Best Underarm Whitening Creams For You 1. J Clin Anesth 2019;54:25-32. Taking licorice along with estrogen might decrease the effects of estrogen. 2020;2020:3727682. View abstract. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats. View abstract. Effects of cerebral ischemia-reperfusion on pharmacokinetic fate of paeoniflorin after intravenous administration of Paeoniae Radix extract in rats. Ngan LT, Moon JK, Shibamoto T, Ahn YJ. I. Elucidation of five new flavonoid constituents from the roots of Glycyrrhiza glabra L. collected in Xinjiang. Effect of glycyrrhizin on viral replication and quasispecies in patients with type C chronic hepatitis. Serra, A., Uehlinger, D. E., Ferrari, P., Dick, B., Frey, B. M., Frey, F. J., and Vogt, B. Glycyrrhetinic Acid decreases plasma potassium concentrations in patients with anuria. View abstract. Harada M, Suzuki M, Ozaki Y. View abstract. Paeonia lactiflora (Chinese peony) and Paeonia brownii (California peony) relax smooth muscle tissue with a particular affinity for the female reproductive tract. Hinoshita F, Ogura Y, Suzuki Y, et al. But not everyone will have the side . CJEM 2010;12(3):224-225. J Clin Psychopharmacol 2016;36(6):572-9. Moreover, it will be necessary to check for recurrence . Sheth, V. M. and Pandya, A. G. Melasma: a comprehensive update: part II. and Glycyrrhiza glabra L. extracts in patients with Familial Mediterranean Fever. Deglycyrrhizinated liquorice in duodenal ulcer. Pulmonary edema following a licorice binge. View abstract. Some of these health benefits have also . View abstract. Mattarello MJ, Karbowiak I, Ermolao A, and et al. Hajiaghamohammadi, A. Tsuda T, Sugaya A, Ohguchi H, et al. Iran J Pharm Res 2012;11(2):541-8. Burgess, J. J Peripher.Nerv.Syst. Eur J Pharmacol 1981;72:219-25.. View abstract. Heidemann HT, Kreuzfelder E. Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment. View abstract. View abstract. View abstract. The dogs treated with the herbal mixture saw a 37.5 percent improvement . View abstract. View abstract. Features : Herbal Energy & Performance: Bronson's Korean Panax Ginseng provides 1000 MG per serving to naturally support energy and physical performance without any unwanted jitters. Peony-glycyrrhiza decoction for antipsychotic-related hyperprolactinemia in women with schizophrenia: a randomized controlled trial. This formula has also been shown to dramatically relieve various types of spasmodic pain such as muscle cramps in the back and legs (restless legs) stiff muscles premenstrual cramping sciatica and abdominal pain. Another type of licorice, called DGL or deglycyrrhizinated licorice, does not seem to have the same side effects and is sometimes used to treat peptic ulcers, canker sores, and reflux (GERD). This week, The New England Journal of Medicine reported that a man with a poor diet died of cardiac arrest after eating a bag-and-a-half of black licorice daily for weeks. Front Psychiatry 2020;11:605949. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. View abstract. In a 30-day study in 50 adults with indigestion, taking a 75-mg licorice . Back to the Blog. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. View abstract. Am J Chin Med 2003;31:445-53. . View abstract. Int Endod.J 2011;44(1):51-58. typica. J Hum Hypertens 1995;9:345-8. J Agric Food Chem 2012;60(36):9062-73. Licorice, tobacco chewing, and hypertension. . View abstract. View abstract. View abstract. Therapeutic Research Faculty 2020. One major reported side effect of licorice root is reduced levels of testosterone in men ( 10 ). View abstract. Ann Pharmacother 2003;37(6):836-838. Yang HO, Ko WK, Kim JY, Ro HS. 2008;9(3):88-98. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. Select a condition to view a list of vitamins. 2010 Nov;35(10):1587-93. The 1:1 of peony and licorice group can significantly reduced the ureteral smooth muscle tension and Christina Loosestrife herb can increase the u reteral tension, but the amount is too large, the mechanism may be related with the diuretic row stone. But I didn't take it long enough to see any change. "It contains liquiritin, an active compound that helps to disperse and remove existing melanin in the skin," explains Chwalek. Gut 1973;14(9):711-715. Low doses of liquorice can induce hypertension encephalopathy. Also for White Peony, the plant that is used in traditional . That's because licorice real black licorice, not the phony licorice-flavored stuff flavored with anise oil . Phytother Res 2008;22(6):709-724. Medicinal herbs: modulation of estrogen action. Let's take a look at the forms, uses, and side effects of . Jia, Y. View abstract. Taking too much licorice can cause high blood pressure. van Beers, E. J., Stam, J., and van den Bergh, W. M. Licorice consumption as a cause of posterior reversible encephalopathy syndrome: a case report. J Clin Endocrinol Metab 2003;88:2384-92. Gallacher SD, Tsokolas G, Dimitropoulos I. Liquorice-induced apparent mineralocorticoid excess presenting in the emergency department. N Engl J Med 1990;322:850. A., Motallebnejad, M., and Khanian, M. The efficacy of the bioadhesive patches containing licorice extract in the management of recurrent aphthous stomatitis. Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial. Part 2: Effect of glycyrrhizic acid on the course of illness]. View abstract. Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. Madisch A, Melderis H, Mayr G, et al. Nussbaumer, U., Landolt, M., Rothlisberger, G., Akovbiantz, A., Keller, H., Weber, E., Blum, A. L., and Peter, P. [Postoperative stress hemorrhage: ineffective prevention with pepsin inhibitor and deglycyrrhizinized licorice extract. View abstract. Hasani-Ranjbar, S., Nayebi, N., Moradi, L., Mehri, A., Larijani, B., and Abdollahi, M. The efficacy and safety of herbal medicines used in the treatment of hyperlipidemia; a systematic review. Arch Pharm Res 2002;25(3):293-299. Chinese herbal medicine for atopic eczema. 2010;16(4):216-218. Westman EC, Guthrie GP. View abstract. WebMD does not provide medical advice, diagnosis or treatment. Hsiu, S. L., Lin, Y. T., Wen, K. C., Hou, Y. C., and Chao, P. D. A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats. View abstract. B. and Tang, T. Q. A., van der Ven, P. F., Martin, M., Sherman, J., and Haley, J. View abstract. J Ethnopharmacol 2021;275:114116. A man in Massachusetts died after eating too much black licorice, which contains a compound known to be toxic in large doses, according to a new report. View abstract. Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. View abstract. 1987;(10):46-48. J Telemed Telecare. View abstract. Takahara T, Watanabe A, Shiraki K. Effects of glycyrrhizin on hepatitis B surface antigen: a biochemical and morphological study. Scali, M., Pratesi, C., Zennaro, M. C., Zampollo, V., and Armanini, D. Pseudohyperaldosteronism from liquorice-containing laxatives. 2007;30(10):1898-1904. It may disrupt the production of sex hormones ( 9 ). View abstract. Int Immunopharmacol. Phytother.Res. View abstract. Steroids 2004;69(11-12):763-766. Zhong.Xi.Yi.Jie.He.Za Zhi. J Endocrinol Invest 1996;19:624-9. van der Zwan A. Efficacy of traditional Chinese herbal therapy in adult atopic dermatitis. Ital J Neurol Sci 1983;4(4):493-497. Menati L, Khaleghinezhad K, Tadayon M, Siahpoosh A. Wang H, Wei W, Wang NP, et al. Med Princ Pract 2010;19(6):485-489. Lee, S. M., Li, M. L., Tse, Y. C., Leung, S. C., Lee, M. M., Tsui, S. K., Fung, K. P., Lee, C. Y., and Waye, M. M. Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway.